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Volixibat potassium

CAS No. 1431935-92-0

Volixibat potassium( SHP-626 | SAR-548304 | LUM-002 )

Catalog No. M11837 CAS No. 1431935-92-0

A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Volixibat potassium
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).
  • Description
    A highly potent and selective inhibitor of the apical sodium-dependent bile acid transporter (ASBT) in development for the treatment of nonalcoholic steatohepatitis (NASH).Steatohepatitis Phase 2 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SHP-626 | SAR-548304 | LUM-002
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    ASBT Transporter
  • Recptor
    ASBT Transporter
  • Research Area
    Other Indications
  • Indication
    Steatohepatitis

Chemical Information

  • CAS Number
    1431935-92-0
  • Formula Weight
    844.045
  • Molecular Formula
    C38H50KN3O12S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ((2R,3R,4S,5R,6R)-4-(benzyloxy)-6-(3-(3-((3S,4R,5R)-3-butyl-7-(dimethylamino)-3-ethyl-4-hydroxy-1,1-dioxido-2,3,4,5-tetrahydrobenzo[b]thiepin-5-yl)phenyl)ureido)-3,5-dihydroxytetrahydro-2H-pyran-2-yl)methyl hydrogen sulfate, potassium salt

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Siebers N, et al. Eur J Drug Metab Pharmacokinet. 2017 Jul 12. doi: 10.1007/s13318-017-0429-7. 2. Tiessen RG, et al. BMC Gastroenterol. 2018 Jan 5;18(1):3.
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